Naproxen exhibits anti - inflammatory, analgesic, and antipyretic activity. The drug inhibits the activity of the enzyme cyclo - oxygenase, resulting in decreased formation of precursors of prostaglandins and thromboxanes from arachidonic acid. Naproxen is readily and completely absorbed from the gastrointestinal (GI) tract after administration. The duration of the analgesic action of Naproxen is up to 7 hours.
Rheumatic disease treatment: the treatment of the acute or chronic rheumatoid arthritis. The relief of acute or chronic osteoarthritis, ankylosing spondylitis, or juvenile arthritis, does not affect the progressive course of arthritic disease. Concurrent treatment with an adrenocoritcoid or a disease - modifying agent may be necessary, depending on the condition being treated and patient response.
The relief of mild to moderate plain, especially when anti - inflammatory actions may also be desired. E.g.., following dental, obstetric, or orthopedic surgery and for the relief of musculoskeletal pain due to soft issue athletic injuries (Strains or sprains). Naproxen is also indicated in the relief of mild to moderate bone pain caused by metastatic neoplastic disease.
The treatment of fever: Naproxen is indicated for reduction of fever.The relief of pain and inflammation of acute gouty arthritis, Naproxen does not correct hyperuricemia.
The treatment of painful nonrheumatic inflammatory conditions, such as: athletic injuries, capsulitis, synovitis, or tenosynovitis.
The relief of the pain and other symptomps of primary dysmenorrheal by initiating therapy as rapidly as possible after the onset of menses. Prophylactic therapy has not been found to provide additional benefit.